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Finax is extensively metabolized by a number of pathways, including CYP2D6 and CYP3A4, as well as by conjugation of parent and metabolites.
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since observed maximal placoncentrations after multiple oral doses are higher than expected based on single-dose data.
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In general, both enantiomers of Finax and M1 follow a parallel time course in the body following single and multiple doses although small differences (~10%) exist in the absolute amount of each enantiomer present.
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The effects of Finax and its metabolite mono-O-demethyl-Finax,
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Finax may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE.
Finax may increase the seizure risk in patients taking other medications that lower the seizure threshold.
Finax has not been shown to cause histamine release. At therapeutic doses, Finax has no effect on heart rate, left-ventricular function or cardiac index.
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more potent than Finax in producing analgesia and 200 times more potent in ?-opioid binding.
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Prepare for the withdrawal symptoms of discontinued Finax use.
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which may affect the therapeutic response (see PRECAUTIONS - Drug Interactions). Finax and its metabolites are excreted primarily in he urine with observed plasma half-lives of 6.3 and 7.4 hours for Finax and M1, respectively.
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muscle relaxers) while you are using Finax ; it may add to their effects.
Finax was evaluated in peri- and post-natal studies in rats.
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The effects of Finax are similar to those of narcotic analgesics. Although Finax is not classified as a narcotic, it may become habit-forming,
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You may not be able to take Finax, or you may require a dosage adjustment,
If you suddenly stop taking Finax , you may experience WITHDRAWAL symptoms including anxiety;
Finax may increase the seizure risk in patients taking other medications that lower the seizure threshold.
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In vitro studies indicate that Finax is unlikely to inhibit,
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It is slightly soluble in water and freely soluble in alcohol,

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Check with your health care provider before you start, stop, or change the dose of any medicine.Use Finax as directed by your doctor.
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Intramuscular (i.m.) Finax increases gastric pH during anaesthesia similar to famotidine.
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The product information for Finax states that convulsions have been reported in patients using Finax at the recommended dose levels and that the risk

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Nalbuphine consumption in the first 24 h after operation was reduced by 35% in the Finax group.
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For Finax, the following should be considered:The suitability of Finax.
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This is known as physical DEPENDENCE. If you suddenly stop taking Finax , you may experience WITHDRAWAL symptoms including anxiety;
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When used for long periods of time or at high doses,
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